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HIF-1α-Overexpressing Mesenchymal Stem Cells Attenuate Colitis by Regulating M1-like Macrophages Polarization toward M2-like Macrophages

A modified mesenchymal stem cell (MSC) transplantation is a highly effective and precise treatment for inflammatory bowel disease (IBD), with a significant curative effect. Thus, we aim to examine the efficacy of hypoxia-inducible factor (HIF)–1α-overexpressing MSC (HIF-MSC) transplantation in exper...

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Detalles Bibliográficos
Autores principales: Zhu, Wenya, Chen, Qianqian, Li, Yi, Wan, Jun, Li, Jia, Tang, Shuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045413/
https://www.ncbi.nlm.nih.gov/pubmed/36979804
http://dx.doi.org/10.3390/biomedicines11030825