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Optimisation and Validation of a conventional ELISA and cut-offs for detecting and quantifying anti-SARS-CoV-2 Spike, RBD, and Nucleoprotein IgG, IgM, and IgA antibodies in Uganda

There is an urgent need for better immunoassays to measure antibody responses as part of immune-surveillance activities and to profile immunological responses to emerging SARS-CoV-2 variants. We optimised and validated an in-house conventional ELISA to identify and quantify SARS-CoV-2 spike- (S-), r...

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Detalles Bibliográficos
Autores principales: Oluka, Gerald Kevin, Namubiru, Patricia, Kato, Laban, Ankunda, Violet, Gombe, Ben, Cotten, Matthew, Musenero, Monica, Kaleebu, Pontiano, Fox, Julie, Serwanga, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045470/
https://www.ncbi.nlm.nih.gov/pubmed/36999017
http://dx.doi.org/10.3389/fimmu.2023.1113194