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Alternative splicing derived invertebrate variable lymphocyte receptor displays diversity and specificity in immune system of crab Eriocheir sinensis

Variable lymphocyte receptors (VLRs) play vital roles in adaptive immune system of agnathan vertebrate. In the present study, we first discover a novel VLR gene, VLR2, from an invertebrate, the Chinese mitten crab, Eriocheir sinensis. VLR2 has ten different isoforms formed via alternative splicing,...

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Detalles Bibliográficos
Autores principales: Xu, Yuanfeng, Yang, Yanan, Zheng, Jinbin, Cui, Zhaoxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045472/
https://www.ncbi.nlm.nih.gov/pubmed/36999166
http://dx.doi.org/10.3389/fimmu.2022.1105318