Computational and Preclinical Analysis of 2-(4-Methyl)benzylidene-4,7-dimethyl Indan-1-one (IPX-18): A Novel Arylidene Indanone Small Molecule with Anti-Inflammatory Activity via NF-κB and Nrf2 Signaling

SIMPLE SUMMARY: Inflammatory responses are recorded in many dreadful diseases. As the presently used mainline anti-inflammatory treatments are proven to have adverse short- and/or long-term side effects, the search for alternative anti-inflammatory agents that may possess lesser side effects is on c...

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Detalles Bibliográficos
Autores principales: Gahtani, Reem M., Shaikh, Ahmad, Kamli, Hossam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045539/
https://www.ncbi.nlm.nih.gov/pubmed/36979695
http://dx.doi.org/10.3390/biomedicines11030716

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045539/
https://www.ncbi.nlm.nih.gov/pubmed/36979695
http://dx.doi.org/10.3390/biomedicines11030716

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