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HAPLN1 confers multiple myeloma cell resistance to several classes of therapeutic drugs

Multiple myeloma (MM), a malignant plasma cell infiltration of the bone marrow, is generally considered incurable: resistance to multiple therapeutic drugs inevitably arises from tumor cell-intrinsic and tumor microenvironment (TME)-mediated mechanisms. Here we report that the proteoglycan tandem re...

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Detalles Bibliográficos
Autores principales: Huynh, Mailee, Chang, Hae Yeun, Lisiero, Dominique N., Ong, Irene M., Kashyap, Trinayan, Callander, Natalie S., Miyamoto, Shigeki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045543/
https://www.ncbi.nlm.nih.gov/pubmed/36480501
http://dx.doi.org/10.1371/journal.pone.0274704