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Ubiquitin-Specific Proteases as Potential Therapeutic Targets in Bladder Cancer—In Vitro Evaluation of Degrasyn and PR-619 Activity Using Human and Canine Models

Background: The inhibition of ubiquitin-specific proteases (USPs) is a novel and promising direction in the development of molecularly targeted therapies in oncology. The aim of the present study was to examine whether Degrasyn could be a potential therapeutic agent against bladder cancer (BC). Also...

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Detalles Bibliográficos
Autores principales: Nowak, Łukasz, Krajewski, Wojciech, Dejnaka, Ewa, Małkiewicz, Bartosz, Szydełko, Tomasz, Pawlak, Aleksandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045593/
https://www.ncbi.nlm.nih.gov/pubmed/36979739
http://dx.doi.org/10.3390/biomedicines11030759