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NEK1-Mediated Phosphorylation of YAP1 Is Key to Prostate Cancer Progression

The key to preventing mCRPC progression is understanding how androgen-dependent PCa cells progress to independence and modify their transcriptional repertoire accordingly. We recently identified a novel axis of the Hippo pathway characterized by the sequential kinase cascade induced by androgen depr...

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Detalles Bibliográficos
Autores principales: Ghosh, Ishita, Khalil, Md Imtiaz, Mirza, Rusella, King, Judy, Olatunde, Damilola, De Benedetti, Arrigo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045622/
https://www.ncbi.nlm.nih.gov/pubmed/36979713
http://dx.doi.org/10.3390/biomedicines11030734