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Inhibiting NLRP3 Inflammasome Activation by CY-09 Helps to Restore Cerebral Glucose Metabolism in 3×Tg-AD Mice

The reduction of the cerebral glucose metabolism is closely related to the activation of the NOD-like receptor protein 3 (NLRP3) inflammasome in Alzheimer’s disease (AD); however, its underlying mechanism remains unclear. In this paper, (18)F-flurodeoxyglucose positron emission tomography was used t...

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Detalles Bibliográficos
Autores principales: Han, Shuangxue, He, Zhijun, Hu, Xia, Li, Xiaoqian, Zheng, Kaixin, Huang, Yingying, Xiao, Peng, Xie, Qingguo, Ni, Jiazuan, Liu, Qiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045645/
https://www.ncbi.nlm.nih.gov/pubmed/36978970
http://dx.doi.org/10.3390/antiox12030722