Synthesis, In Vitro Biological Evaluation of Antiproliferative and Neuroprotective Effects and In Silico Studies of Novel 16E-Arylidene-5α,6α-epoxyepiandrosterone Derivatives

Steroids constitute an important class of pharmacologically active molecules, playing key roles in human physiology. Within this group, 16E-arylideneandrostane derivatives have been reported as potent anti-cancer agents for the treatment of leukemia, breast and prostate cancers, and brain tumors. Ad...

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Detalles Bibliográficos
Autores principales: Brito, Vanessa, Marques, Mariana, Esteves, Marta, Serra-Almeida, Catarina, Alves, Gilberto, Almeida, Paulo, Bernardino, Liliana, Silvestre, Samuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045663/
https://www.ncbi.nlm.nih.gov/pubmed/36979790
http://dx.doi.org/10.3390/biomedicines11030812

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045663/
https://www.ncbi.nlm.nih.gov/pubmed/36979790
http://dx.doi.org/10.3390/biomedicines11030812

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