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DJ-1 Deficiency Protects against Sepsis-Induced Myocardial Depression

Oxidative stress is considered one of the early underlying contributors of sepsis-induced myocardial depression. DJ-1, also known as PARK7, has a well-established role as an antioxidant. We have previously shown, in a clinically relevant model of polymicrobial sepsis, DJ-1 deficiency improved surviv...

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Detalles Bibliográficos
Autores principales: Tsoporis, James N., Amatullah, Hajera, Gupta, Sahil, Izhar, Shehla, Ektesabi, Amin M., Vaswani, Chirag M., Desjardins, Jean-Francois, Kabir, Golam, Teixera Monteiro, Ana Paula, Varkouhi, Amir K., Kavantzas, Nikolaos, Salpeas, Vasileios, Rizos, Ioannis, Marshall, John C., Parker, Thomas G., Leong-Poi, Howard, dos Santos, Claudia C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045744/
https://www.ncbi.nlm.nih.gov/pubmed/36978809
http://dx.doi.org/10.3390/antiox12030561