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Bag-1 Protects Nucleus Pulposus Cells from Oxidative Stress by Interacting with HSP70

Bcl-2-associated athanogene 1 (Bag-1) is a multifunctional prosurvival protein that binds to several intracellular targets and promotes cell survival. HSP70 and Raf-1 are important targets of Bag-1; however, the protective function of Bag-1 in nucleus pulposus (NP) cells remains unclear. In this stu...

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Detalles Bibliográficos
Autores principales: Suyama, Kaori, Sakai, Daisuke, Hayashi, Shogo, Qu, Ning, Terayama, Hayato, Kiyoshima, Daisuke, Nagahori, Kenta, Watanabe, Masahiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045753/
https://www.ncbi.nlm.nih.gov/pubmed/36979842
http://dx.doi.org/10.3390/biomedicines11030863