Evaluation of CDK9 Inhibition by Dinaciclib in Combination with Apoptosis Modulating izTRAIL for the Treatment of Colorectal Cancer

Treatment options for colorectal cancer (CRC), especially in advanced stages are still insufficient. There, the discovery of Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) was a bright spot. However, most cancers show resistance toward apoptotic signals. Cyclin-dependent kinas...

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Detalles Bibliográficos
Autores principales: Shen, Xiao, Kretz, Anna-Laura, Schneider, Sandra, Knippschild, Uwe, Henne-Bruns, Doris, Kornmann, Marko, Lemke, Johannes, Traub, Benno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045754/
https://www.ncbi.nlm.nih.gov/pubmed/36979907
http://dx.doi.org/10.3390/biomedicines11030928

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045754/
https://www.ncbi.nlm.nih.gov/pubmed/36979907
http://dx.doi.org/10.3390/biomedicines11030928

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