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LMP2 deficiency causes abnormal metabolism, oxidative stress, neuroinflammation, myelin loss and neurobehavioral dysfunctions
BACKGROUND: Substantial evidence suggests that immunoproteasome is implicated in the various neurological diseases such as stroke, multiple sclerosis and neurodegenerative diseases. However, whether the immunoproteasome itself deficiency causes brain disease is still unclear. Therefore, the aim of t...
Autores principales: | Chen, Xingyong, Mao, Yanguang, Guo, Yueting, Xiao, Dongyun, Lin, Zejing, Huang, Yiyi, Liu, Ying Chun, Zhang, Xu, Wang, Yinzhou |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045813/ https://www.ncbi.nlm.nih.gov/pubmed/36978132 http://dx.doi.org/10.1186/s12967-023-04071-0 |
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