Suppression of Platelet-Derived Growth Factor Receptor-Alpha Overcomes Resistance to Trastuzumab through STAT3-Dependent IL-6 Reduction in HER2-Positive Breast Cancer Cells

Platelet-derived growth factor receptor (PDGFR) plays an essential role in the proliferation and invasion of malignant cancer cells. However, the functional role of PDGFR alpha (PDGFRA) in HER2-positive (HER2+) breast cancer has not been fully clarified yet. Thus, the objective of this study was to...

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Detalles Bibliográficos
Autores principales: Kim, Sangmin, Kim, Hyungjoo, Jeong, Yisun, You, Daeun, Yoon, Sun Young, Lo, Eunji, Nam, Seok Jin, Lee, Jeong Eon, Kim, Seok Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045855/
https://www.ncbi.nlm.nih.gov/pubmed/36979654
http://dx.doi.org/10.3390/biomedicines11030675

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045855/
https://www.ncbi.nlm.nih.gov/pubmed/36979654
http://dx.doi.org/10.3390/biomedicines11030675

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