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Could Local Application of Hypoxia Inducible Factor 1-α Enhancer Deferoxamine Be Promising for Preventing of Medication-Related Osteonecrosis of the Jaw?

This experimental study investigates the prophylactic effect of deferoxamine (DFO) on medication-related osteonecrosis of the jaw (MRONJ). Thirty-six female Sprague Dawley rats received zoledronic acid (ZA) for eight weeks to create an osteonecrosis model. DFO was locally applied into the extraction...

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Detalles Bibliográficos
Autores principales: Yalcin-Ülker, Gül Merve, Günbatan, Murat, Duygu, Gonca, Soluk-Tekkesin, Merva, Özcakir-Tomruk, Ceyda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045901/
https://www.ncbi.nlm.nih.gov/pubmed/36979736
http://dx.doi.org/10.3390/biomedicines11030758