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Estimating individualized treatment effects from randomized controlled trials: a simulation study to compare risk-based approaches

BACKGROUND: Baseline outcome risk can be an important determinant of absolute treatment benefit and has been used in guidelines for “personalizing” medical decisions. We compared easily applicable risk-based methods for optimal prediction of individualized treatment effects. METHODS: We simulated RC...

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Detalles Bibliográficos
Autores principales: Rekkas, Alexandros, Rijnbeek, Peter R., Kent, David M., Steyerberg, Ewout W., van Klaveren, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045909/
https://www.ncbi.nlm.nih.gov/pubmed/36977990
http://dx.doi.org/10.1186/s12874-023-01889-6