Cargando…
Estimating individualized treatment effects from randomized controlled trials: a simulation study to compare risk-based approaches
BACKGROUND: Baseline outcome risk can be an important determinant of absolute treatment benefit and has been used in guidelines for “personalizing” medical decisions. We compared easily applicable risk-based methods for optimal prediction of individualized treatment effects. METHODS: We simulated RC...
Autores principales: | Rekkas, Alexandros, Rijnbeek, Peter R., Kent, David M., Steyerberg, Ewout W., van Klaveren, David |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045909/ https://www.ncbi.nlm.nih.gov/pubmed/36977990 http://dx.doi.org/10.1186/s12874-023-01889-6 |
Ejemplares similares
-
A standardized framework for risk-based assessment of treatment effect heterogeneity in observational healthcare databases
por: Rekkas, Alexandros, et al.
Publicado: (2023) -
Predictive approaches to heterogeneous treatment effects: a scoping review
por: Rekkas, Alexandros, et al.
Publicado: (2020) -
Validation of prediction models: examining temporal and geographic stability of baseline risk and estimated covariate effects
por: Austin, Peter C., et al.
Publicado: (2017) -
Assessing discriminative ability of risk models in clustered data
por: van Klaveren, David, et al.
Publicado: (2014) -
The calibrated model-based concordance improved assessment of discriminative ability in patient clusters of limited sample size
por: van Klaveren, David, et al.
Publicado: (2019)