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Safety, Tolerability, and Immunogenicity of V160, a Conditionally Replication-Defective Cytomegalovirus Vaccine, in Healthy Japanese Men in a Randomized, Controlled Phase 1 Study

Cytomegalovirus (CMV) infection can cause newborn morbidity and mortality; no pharmacological method of reducing CMV infection during pregnancy is currently available. In a phase 1 study in the United States, V160, a conditionally replication-defective CMV vaccine, was immunogenic and well tolerated...

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Detalles Bibliográficos
Autores principales: Murata, Shinya, Oshima, Nobuyuki, Iwasa, Takashi, Fukao, Yukako, Sawata, Miyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045923/
https://www.ncbi.nlm.nih.gov/pubmed/36975369
http://dx.doi.org/10.3390/antib12010022