Integrated Proteomics Unveils Nuclear PDE3A2 as a Regulator of Cardiac Myocyte Hypertrophy

Signaling by cAMP is organized in multiple distinct subcellular nanodomains regulated by cAMP-hydrolyzing PDEs (phosphodiesterases). Cardiac β-adrenergic signaling has served as the prototypical system to elucidate cAMP compartmentalization. Although studies in cardiac myocytes have provided an unde...

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Detalles Bibliográficos
Autores principales: Subramaniam, Gunasekaran, Schleicher, Katharina, Kovanich, Duangnapa, Zerio, Anna, Folkmanaite, Milda, Chao, Ying-Chi, Surdo, Nicoletta C., Koschinski, Andreas, Hu, Jianshu, Scholten, Arjen, Heck, Albert J.R., Ercu, Maria, Sholokh, Anastasiia, Park, Kyung Chan, Klussmann, Enno, Meraviglia, Viviana, Bellin, Milena, Zanivan, Sara, Hester, Svenja, Mohammed, Shabaz, Zaccolo, Manuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045983/
https://www.ncbi.nlm.nih.gov/pubmed/36883446
http://dx.doi.org/10.1161/CIRCRESAHA.122.321448

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10045983/
https://www.ncbi.nlm.nih.gov/pubmed/36883446
http://dx.doi.org/10.1161/CIRCRESAHA.122.321448

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