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Rosiglitazone Mitigates Dexamethasone-Induced Depression in Mice via Modulating Brain Glucose Metabolism and AMPK/mTOR Signaling Pathway

Major depressive disorder (MDD) is a common, complex disease with poorly understood pathogenesis. Disruption of glucose metabolism is implicated in the pathogenesis of depression. AMP-activated protein kinase (AMPK) has been shown to regulate the activity of several kinases, including pAKT, p38MAPK,...

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Detalles Bibliográficos
Autores principales: Alhaddad, Aisha, Radwan, Asmaa, Mohamed, Noha A., Mehanna, Eman T., Mostafa, Yasser M., El-Sayed, Norhan M., Fattah, Shaimaa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046017/
https://www.ncbi.nlm.nih.gov/pubmed/36979839
http://dx.doi.org/10.3390/biomedicines11030860