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Aberrant HMGA2 Expression Sustains Genome Instability That Promotes Metastasis and Therapeutic Resistance in Colorectal Cancer

SIMPLE SUMMARY: Despite recent advances in early diagnostic and therapeutic strategies, colorectal cancer remains one of the most diagnosed and lethal cancers worldwide. Further, several patients are diagnosed at late stages with metastatic disease, ultimately limiting their therapeutic options. To...

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Detalles Bibliográficos
Autores principales: Campos Gudiño, Rubi, McManus, Kirk J., Hombach-Klonisch, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046046/
https://www.ncbi.nlm.nih.gov/pubmed/36980621
http://dx.doi.org/10.3390/cancers15061735