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Knockdown SENP1 Suppressed the Angiogenic Potential of Mesenchymal Stem Cells by Impacting CXCR4-Regulated MRTF-A SUMOylation and CCN1 Expression

The angiogenic potential of mesenchymal stem cells (MSCs) is critical for adult vascular regeneration and repair, which is regulated by various growth factors and cytokines. In the current study, we report that knockdown SUMO-specific peptidase 1 (SENP1) stimulated the SUMOylation of MRTF-A and prev...

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Detalles Bibliográficos
Autores principales: Zhang, Rui, Liu, Qingxi, Lyu, Cuicui, Gao, Xing, Ma, Wenjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046070/
https://www.ncbi.nlm.nih.gov/pubmed/36979893
http://dx.doi.org/10.3390/biomedicines11030914