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Therapeutic Drug Monitoring in Oncohematological Patients: A Fast and Accurate HPLC-UV Method for the Quantification of Nilotinib in Human Plasma and Its Clinical Application

Nilotinib, a second-generation tyrosine kinase inhibitor, has demonstrated clinical activity in chronic myeloid leukemia. As an exposure–response relationship has been observed for nilotinib, its therapeutic drug monitoring could be a valuable tool in clinical practice. Therefore, the aim of this st...

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Detalles Bibliográficos
Autores principales: Escudero-Ortiz, Vanesa, Rodríguez-Lucena, Francisco José, Estan-Cerezo, Gabriel, Mancheño-Maciá, Esther, Conesa-García, Venancio, García-Monsalve, Ana, Soriano-Irigaray, Leticia, Navarro-Ruiz, Andrés
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046071/
https://www.ncbi.nlm.nih.gov/pubmed/36979926
http://dx.doi.org/10.3390/biomedicines11030947