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Therapeutic Drug Monitoring in Oncohematological Patients: A Fast and Accurate HPLC-UV Method for the Quantification of Nilotinib in Human Plasma and Its Clinical Application
Nilotinib, a second-generation tyrosine kinase inhibitor, has demonstrated clinical activity in chronic myeloid leukemia. As an exposure–response relationship has been observed for nilotinib, its therapeutic drug monitoring could be a valuable tool in clinical practice. Therefore, the aim of this st...
Autores principales: | Escudero-Ortiz, Vanesa, Rodríguez-Lucena, Francisco José, Estan-Cerezo, Gabriel, Mancheño-Maciá, Esther, Conesa-García, Venancio, García-Monsalve, Ana, Soriano-Irigaray, Leticia, Navarro-Ruiz, Andrés |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046071/ https://www.ncbi.nlm.nih.gov/pubmed/36979926 http://dx.doi.org/10.3390/biomedicines11030947 |
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