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An Efficient Bayesian Method for Estimating the Degree of the Skewness of X Chromosome Inactivation Based on the Mixture of General Pedigrees and Unrelated Females

Skewed X chromosome inactivation (XCI-S) has been reported to be associated with some X-linked diseases. Several methods have been proposed to estimate the degree of XCI-S (denoted as [Formula: see text]) for quantitative and qualitative traits based on unrelated females. However, there is no method...

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Detalles Bibliográficos
Autores principales: Kong, Yi-Fan, Li, Shi-Zhu, Wang, Kai-Wen, Zhu, Bin, Yuan, Yu-Xin, Li, Meng-Kai, Zhou, Ji-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046098/
https://www.ncbi.nlm.nih.gov/pubmed/36979477
http://dx.doi.org/10.3390/biom13030543