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Dopamine Dynamics and Neurobiology of Non-Response to Antipsychotics, Relevance for Treatment Resistant Schizophrenia: A Systematic Review and Critical Appraisal

Treatment resistant schizophrenia (TRS) is characterized by a lack of, or suboptimal response to, antipsychotic agents. The biological underpinnings of this clinical condition are still scarcely understood. Since all antipsychotics block dopamine D2 receptors (D2R), dopamine-related mechanisms shoul...

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Detalles Bibliográficos
Autores principales: Iasevoli, Felice, Avagliano, Camilla, D’Ambrosio, Luigi, Barone, Annarita, Ciccarelli, Mariateresa, De Simone, Giuseppe, Mazza, Benedetta, Vellucci, Licia, de Bartolomeis, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046109/
https://www.ncbi.nlm.nih.gov/pubmed/36979877
http://dx.doi.org/10.3390/biomedicines11030895