LL-37 Might Promote Local Invasion of Melanoma by Activating Melanoma Cells and Tumor-Associated Macrophages

SIMPLE SUMMARY: LL-37 contributes the vertical invasion of tumor cells in melanoma. Indeed, the ratio of LL-37-expressing cells correlated positively to T stage severity. Moreover, LL-37 induced pro-angiogenic factors in both human and mouse systems. Our results suggested that LL-37 stimulates both...

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Detalles Bibliográficos
Autores principales: Ohuchi, Kentaro, Ikawa, Tetsuya, Amagai, Ryo, Takahashi, Toshiya, Roh, Yuna, Endo, Junko, Kambayashi, Yumi, Asano, Yoshihide, Fujimura, Taku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046113/
https://www.ncbi.nlm.nih.gov/pubmed/36980564
http://dx.doi.org/10.3390/cancers15061678

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046113/
https://www.ncbi.nlm.nih.gov/pubmed/36980564
http://dx.doi.org/10.3390/cancers15061678

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