Mechanotransduction Impairment in Primary Fibroblast Model of Krabbe Disease

Krabbe disease (KD) is a genetic disorder caused by the absence of the galactosylceramidase (GALC) functional enzyme. No cure is currently available. Here, we investigate the mechanotransduction process in primary fibroblasts collected from the twitcher mouse, a natural KD murine model. Thanks to me...

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Detalles Bibliográficos
Autores principales: Mezzena, Roberta, Del Grosso, Ambra, Pellegrino, Roberto Maria, Alabed, Husam B. R., Emiliani, Carla, Tonazzini, Ilaria, Cecchini, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046230/
https://www.ncbi.nlm.nih.gov/pubmed/36979906
http://dx.doi.org/10.3390/biomedicines11030927

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046230/
https://www.ncbi.nlm.nih.gov/pubmed/36979906
http://dx.doi.org/10.3390/biomedicines11030927

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