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Elucidation of DNA-Eltrombopag Binding: Electrochemical, Spectroscopic and Molecular Docking Techniques

Eltrombopag is a powerful adjuvant anticancer drug used in treating MS (myelodysplastic syndrome) and AML (acute myeloid leukemia) diseases. In this study, the interaction mechanism between eltrombopag and DNA was studied by voltammetry, spectroscopic techniques, and viscosity measurements. We devel...

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Detalles Bibliográficos
Autores principales: Cheraghi, Somaye, Şenel, Pelin, Dogan Topal, Burcu, Agar, Soykan, Majidian, Mahsa, Yurtsever, Mine, Bellur Atici, Esen, Gölcü, Ayşegül, Ozkan, Sibel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046231/
https://www.ncbi.nlm.nih.gov/pubmed/36979512
http://dx.doi.org/10.3390/bios13030300