Cargando…

Elucidation of DNA-Eltrombopag Binding: Electrochemical, Spectroscopic and Molecular Docking Techniques

Eltrombopag is a powerful adjuvant anticancer drug used in treating MS (myelodysplastic syndrome) and AML (acute myeloid leukemia) diseases. In this study, the interaction mechanism between eltrombopag and DNA was studied by voltammetry, spectroscopic techniques, and viscosity measurements. We devel...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cheraghi, Somaye, Şenel, Pelin, Dogan Topal, Burcu, Agar, Soykan, Majidian, Mahsa, Yurtsever, Mine, Bellur Atici, Esen, Gölcü, Ayşegül, Ozkan, Sibel A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046231/ https://www.ncbi.nlm.nih.gov/pubmed/36979512 http://dx.doi.org/10.3390/bios13030300

Ejemplares similares

Detection of Axitinib Using Multiwalled Carbon Nanotube-Fe(2)O(3)/Chitosan Nanocomposite-Based Electrochemical Sensor and Modeling with Density Functional Theory
por: Cetinkaya, Ahmet, et al.
Publicado: (2022)

Electrochemical, spectroscopic, and molecular docking studies of the interaction between the anti-retroviral drug indinavir and dsDNA
por: Mollarasouli, Fariba, et al.
Publicado: (2020)

Mechanism of Interactions of dsDNA Binding with Apigenin and Its Sulfamate Derivatives Using Multispectroscopic, Voltammetric, and Molecular Docking Studies
por: Waihenya, Simon, et al.
Publicado: (2021)

Identification, synthesis and characterization of process related impurities of benidipine hydrochloride, stress-testing/stability studies and HPLC/UPLC method validations()
por: Bellur Atici, Esen, et al.
Publicado: (2015)

Identification, synthesis and characterization of process related desfluoro impurity of ezetimibe and HPLC method validations()
por: Bellur Atici, Esen, et al.
Publicado: (2015)

The Interaction between DNA and Three Intercalating Anthracyclines Using Electrochemical DNA Nanobiosensor Based on Metal Nanoparticles Modified Screen-Printed Electrode
por: Karadurmus, Leyla, et al.
Publicado: (2021)

Spectrophotometric Determination of Metoprolol Tartrate in Pharmaceutical Dosage Forms on Complex Formation with Cu(II)
por: Cesme, Mustafa, et al.
Publicado: (2011)

Sample Stacking–Capillary Electrophoretic Analysis of Nitrate and Nitrite in Organic- and Conventional-Originated Baby Food Formulas from Turkey
por: Kamilova, Nigar, et al.
Publicado: (2023)

Eltrombopag in Good's Syndrome
por: Kristiansen, Håvard Anton, et al.
Publicado: (2014)

Efficacy of eltrombopag in thrombocytopenia after hematopoietic stem cell transplantation
por: KARATAŞ, Ayşe, et al.
Publicado: (2022)

Comparison of Splenectomy and Eltrombopag Treatment in the Second-Line Treatment of Immune Thrombocytopenic Purpura
por: Uğur, Mehmet Can, et al.
Publicado: (2021)

Eltrombopag for the Treatment of Immune Thrombocytopenia: The Aegean Region of Turkey Experience
por: Özdemirkıran, Füsun, et al.
Publicado: (2015)

Scientometric analysis of medicinal leech therapy
por: Şenel, Engin, et al.
Publicado: (2020)

The Eltrombopag antitumor effect on hepatocellular carcinoma
por: KUROKAWA, TOMOHIRO, et al.
Publicado: (2015)

Multiple thrombosis during eltrombopag therapy
por: Shimazu, Yutaka, et al.
Publicado: (2021)

Exploring the Potential of Eltrombopag: Room for More?
por: Tarantini, Francesco, et al.
Publicado: (2022)

Treatment of immune thrombocytopenic purpura: focus on eltrombopag
por: Rice, Lawrence
Publicado: (2009)

Eltrombopag for the treatment of aplastic anemia: current perspectives
por: Lum, Su Han, et al.
Publicado: (2016)

Eltrombopag in long‐term management of pediatric thrombocytopenia
por: Shah, Sanjay J., et al.
Publicado: (2018)

Aplastic Anemia Treated with Eltrombopag during Pregnancy
por: Suminaga, Yuri, et al.
Publicado: (2022)

Pharmacokinetic Evaluation of Eltrombopag in ITP Pediatric Patients
por: Dionisi, Marco, et al.
Publicado: (2021)

Adding eltrombopag to immunosuppression: the importance of predicting outcome
por: Tichelli, André, et al.
Publicado: (2022)

Eltrombopag directly activates BAK and induces apoptosis
por: Chen, Meng, et al.
Publicado: (2023)

Coffee Colored Serum, Adverse Reaction of Eltrombopag
por: Rojas, Carlos Rodríguez, et al.
Publicado: (2023)

Outcomes of Eltrombopag Treatment and Development of Iron Deficiency in Children with Immune Thrombocytopenia in Turkey
por: Koca Yozgat, Ayça, et al.
Publicado: (2020)

Elucidating the Mechanism of Action of the Attributed Immunomodulatory Role of Eltrombopag in Primary Immune Thrombocytopenia: An In Silico Approach
por: Lozano, Maria L., et al.
Publicado: (2021)

Eltrombopag: the emerging evidence of its therapeutic value in thrombocytopenia
por: Profit, Louise
Publicado: (2006)

Severe Thrombotic Complication of Eltrombopag in a Cirrhotic Patient
por: Baumann, Alexandra J., et al.
Publicado: (2016)

Efficacy and safety of eltrombopag in adult refractory immune thrombocytopenia
por: Kim, Yeo-Kyeoung, et al.
Publicado: (2015)

Spotlight on eltrombopag in the treatment of children with chronic immune thrombocytopenia
por: Lambert, Michele P
Publicado: (2016)

Eltrombopag treatment of a dog with idiopathic aplastic pancytopenia
por: Kelly, Darren, et al.
Publicado: (2020)

Eltrombopag directly inhibits BAX and prevents cell death
por: Spitz, Adam Z., et al.
Publicado: (2021)

Preparation and Solid-State Characterization of Eltrombopag Crystal Phases
por: Abbinante, Vincenzo Mirco, et al.
Publicado: (2020)

Repurposing Eltrombopag for Multidrug Resistant Staphylococcus aureus Infections
por: Lee, Hyunjung, et al.
Publicado: (2021)

Eltrombopag for refractory vaccine-induced immune thrombotic thrombocytopenia
por: Maraziti, Giorgio, et al.
Publicado: (2021)

Eltrombopag improves refractory thrombocytopenia in patients with Sjögren's syndrome
por: Xu, Liping, et al.
Publicado: (2022)

Controlled synthesis and computational analysis of gold nanostars for the treatment of Fusarium oxysporum
por: Eshun, Gaddi B., et al.
Publicado: (2023)

Holistic Analysis of Coronavirus Literature: A Scientometric Study of the Global Publications Relevant to SARS-CoV-2 (COVID-19), MERS-CoV (MERS) and SARS-CoV (SARS)
por: Şenel, Engin, et al.
Publicado: (2020)

Considerations in the Management of Hepatitis C Virus-related Thrombocytopenia with Eltrombopag
por: Danish, Fazal A., et al.
Publicado: (2010)

The role of eltrombopag in the management of hepatitis C virus-related thrombocytopenia
por: Danish, Fazal-i-Akbar, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_uo3sjv3c0c8a52e754ibirnav4