Use of Next Generation Sequencing to Define the Origin of Primary Myelofibrosis

SIMPLE SUMMARY: The cell of origin (a stem cell) of primary myelofibrosis (PMF) is still partially unknown. We used next generation sequencing to explore this aspect of PMF pathobiology deeper. We found evidence that higher progenitors (i.e., pluripotent stem cells) harbor genetic lesions found in P...

Descripción completa

Detalles Bibliográficos
Autores principales: Visani, Giuseppe, Etebari, Maryam, Fuligni, Fabio, Di Guardo, Antonio, Isidori, Alessandro, Loscocco, Federica, Paolini, Stefania, Navari, Mohsen, Piccaluga, Pier Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046249/
https://www.ncbi.nlm.nih.gov/pubmed/36980671
http://dx.doi.org/10.3390/cancers15061785

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046249/
https://www.ncbi.nlm.nih.gov/pubmed/36980671
http://dx.doi.org/10.3390/cancers15061785

Ejemplares similares