Computational Insights into the Allosteric Modulation of a Phthalate-Degrading Hydrolase by Distal Mutations

Phthalate esters (PAEs) are a ubiquitous kind of environmental endocrine that disrupt chemicals, causing environmental and health issues. EstJ6 is an effective phthalate-degrading hydrolase, and its mutant with a combination of three non-conservative distal mutations has an improved activity against...

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Detalles Bibliográficos
Autores principales: Xu, Ran, Bao, Yiqiong, Li, Mengrong, Zhang, Yan, Xi, Lili, Guo, Jingjing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046322/
https://www.ncbi.nlm.nih.gov/pubmed/36979378
http://dx.doi.org/10.3390/biom13030443

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046322/
https://www.ncbi.nlm.nih.gov/pubmed/36979378
http://dx.doi.org/10.3390/biom13030443

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