Analysis of Cancer Genomic Amplifications Identifies Druggable Collateral Dependencies within the Amplicon

SIMPLE SUMMARY: Genomic amplifications are highly prevalent in cancer and often contribute to increased proliferation or cell survival upon the administration of anti-cancer drugs. The identification of those amplified genes at which cancer cells are selectively dependent is crucial for the developm...

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Detalles Bibliográficos
Autores principales: Pons, Guillem, Gallo-Oller, Gabriel, Navarro, Natalia, Zarzosa, Patricia, Sansa-Girona, Júlia, García-Gilabert, Lia, Magdaleno, Ainara, Segura, Miguel F., Sánchez de Toledo, Josep, Gallego, Soledad, Moreno, Lucas, Roma, Josep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046350/
https://www.ncbi.nlm.nih.gov/pubmed/36980521
http://dx.doi.org/10.3390/cancers15061636

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046350/
https://www.ncbi.nlm.nih.gov/pubmed/36980521
http://dx.doi.org/10.3390/cancers15061636

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