Cargando…

Structural and Dynamic Differences between Calreticulin Mutants Associated with Essential Thrombocythemia

Essential thrombocythemia (ET) is a blood cancer. ET is characterized by an overproduction of platelets that can lead to thrombosis formation. Platelet overproduction occurs in megakaryocytes through a signaling pathway that could involve JAK2, MPL, or CALR proteins. CALR mutations are associated wi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Radjasandirane, Ragousandirane, de Brevern, Alexandre G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046389/ https://www.ncbi.nlm.nih.gov/pubmed/36979444 http://dx.doi.org/10.3390/biom13030509

Ejemplares similares

Mutant calreticulin causes essential thrombocythemia
por: Shimoda, Kazuya, et al.
Publicado: (2017)

Calreticulin mutant mice develop essential thrombocythemia that is ameliorated by the JAK inhibitor ruxolitinib
por: Shide, K, et al.
Publicado: (2017)

Alterations of Signaling Pathways in Essential Thrombocythemia with Calreticulin Mutation
por: Hui, Wuhan, et al.
Publicado: (2021)

Comparison of Clinical and Hematological Parameters of Janus Kinase 2, Calreticulin or Myeloproliferative Leukemia Virus Oncogene Mutant Essential Thrombocythemia and Triple-Negative Essential Thrombocythemia
por: Yıldız, Jale, et al.
Publicado: (2022)

Calreticulin Mutated Essential Thrombocythemia Presenting as Acute Coronary Syndrome
por: Nazha, Bassel, et al.
Publicado: (2015)

Calreticulin in Essential Thrombocythemia: StressINg OUT the Megakaryocyte Nucleus
por: Iborra, Francisco Jose, et al.
Publicado: (2017)

Two Novel Monoallelic Calreticulin Mutations in a Patient With Essential Thrombocythemia
por: Kamory, Eniko, et al.
Publicado: (2017)

Rebound of platelet count in a patient with type 2 calreticulin-mutant essential thrombocythemia in the postpartum period: A case report
por: Al-Mashdali, Abdulrahman F., et al.
Publicado: (2021)

Essential thrombocythemia with (type2) calreticulin presented as stuttering priapism case report and review of literature
por: Ali, Elrazi Awadelkarim, et al.
Publicado: (2020)

Hematological relevance of JAK2 V617F and calreticulin mutations in Tunisian patients with essential thrombocythemia
por: Abdelghani, Maroua, et al.
Publicado: (2022)

Myocardial Infarction as an Initial Presentation of Essential Thrombocythemia With Calreticulin (CALR) Mutation (None Type 1, None Type 2)
por: Afana, Mohammad, et al.
Publicado: (2023)

Essential thrombocythemia
por: Brière, Jean B
Publicado: (2007)

Thrombophilic Risk of Factor V Leiden, Prothrombin G20210A, MTHFR, and Calreticulin Mutations in Essential Thrombocythemia Egyptian Patients
por: El-Ghonemy, Mohamed S., et al.
Publicado: (2020)

Mutant Calreticulin in the Myeloproliferative Neoplasms
por: Prins, Daniel, et al.
Publicado: (2020)

Ruxolitinib for essential thrombocythemia?
por: Bose, Prithviraj, et al.
Publicado: (2017)

Dynamics of mutations in patients with essential thrombocythemia treated with imetelstat
por: Leibundgut, Elisabeth Oppliger, et al.
Publicado: (2020)

Clinical Manifestation of Calreticulin Gene Mutations in Essential Thrombocythemia without Janus Kinase 2 and MPL Mutations: A Chinese Cohort Clinical Study
por: Sun, Chao, et al.
Publicado: (2016)

Calreticulin Is Essential for Cardiac Development
por: Mesaeli, Nasrin, et al.
Publicado: (1999)

Emerging treatments for essential thrombocythemia
por: Okoli, Steven, et al.
Publicado: (2011)

Thromboembolic complication in Essential Thrombocythemia
por: Mozaheb, Zahra
Publicado: (2012)

Essential thrombocythemia: Busulphan revisited
por: Koduri, Prasad R.
Publicado: (2016)

Ruxolitinib for the Treatment of Essential Thrombocythemia
por: Gunawan, Arief, et al.
Publicado: (2018)

Essential Thrombocythemia in Children and Adolescents
por: Putti, Maria Caterina, et al.
Publicado: (2021)

Mutations and thrombosis in essential thrombocythemia
por: Guglielmelli, Paola, et al.
Publicado: (2021)

Generalized granuloma annulare associated with essential thrombocythemia
por: Polineni, Sai P., et al.
Publicado: (2020)

Focal Segmental Glomerulosclerosis Associated with Essential Thrombocythemia
por: Sugimoto, Hisashi, et al.
Publicado: (2022)

Secreted calreticulin mutants subvert anticancer immunosurveillance
por: Liu, Peng, et al.
Publicado: (2019)

Moyamoya syndrome in an adult with essential thrombocythemia
por: Lazzaro, Marc A., et al.
Publicado: (2011)

Essential thrombocythemia: Rare cause of chorea
por: Venkatesan, Eswaradass Prasanna, et al.
Publicado: (2014)

Essential thrombocythemia treatment algorithm 2018
por: Tefferi, Ayalew, et al.
Publicado: (2018)

Essential Thrombocythemia Presenting as Paraneoplastic Glomerulonephritis
por: Abdulla, M. C., et al.
Publicado: (2018)

Secreted mutant calreticulins as rogue cytokines in myeloproliferative neoplasms
por: Pecquet, Christian, et al.
Publicado: (2023)

Differences in Hematological and Clinical Features Between Essential Thrombocythemia Cases With JAK2- or CALR-Mutations
por: Kubuki, Yoko, et al.
Publicado: (2017)

Cerebral Dissecting Aneurysms in Patients with Essential Thrombocythemia
por: Baek, Jin Wook, et al.
Publicado: (2014)

Essential thrombocythemia: a rare disease in childhood
por: Beatrice, Julia Maimone, et al.
Publicado: (2013)

Recent advances in understanding myelofibrosis and essential thrombocythemia
por: Vainchenker, William, et al.
Publicado: (2016)

Thiol-disulphide Homeostasis in Essential Thrombocythemia Patients
por: Yıkılmaz, Aysun Şentürk, et al.
Publicado: (2019)

Updates in the management of polycythemia vera and essential thrombocythemia
por: Bose, Prithviraj, et al.
Publicado: (2019)

Essential thrombocythemia manifesting as ophthalmic artery occlusion
por: Thabsuwan, Kittipong, et al.
Publicado: (2020)

Limb gangrene: The first sign of essential thrombocythemia
por: Bolaman, Ali Zahit, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_sbeffmnee3atojn7nus64cpav7