Cargando…

Deregulated Gene Expression Profiles and Regulatory Networks in Adult and Pediatric RUNX1/RUNX1T1-Positive AML Patients

SIMPLE SUMMARY: AML is a heterogeneous and complex disease. RUNX1/RUNX1T1 is a fusion oncogene resulting from the chromosomal translocation t(8;21) and plays a crucial role in AML. However, its impact on the transcriptomic profile of different age groups among AML patients is not completely understo...

Descripción completa

Detalles Bibliográficos
Autores principales: Kanellou, Peggy, Georgakopoulos-Soares, Ilias, Zaravinos, Apostolos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046396/
https://www.ncbi.nlm.nih.gov/pubmed/36980682
http://dx.doi.org/10.3390/cancers15061795