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G-Quadruplexes in c-MYC Promoter as Targets for Cancer Therapy

Cancer is a societal burden demanding innovative approaches. A major problem with the conventional chemotherapeutic agents is their strong toxicity and other side effects due to their poor selectivity. Uncontrolled proliferation of cancer cells is due to mutations, deletions, or amplifications in ge...

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Detalles Bibliográficos
Autores principales: Bahls, Bárbara, Aljnadi, Israa M., Emídio, Rita, Mendes, Eduarda, Paulo, Alexandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046398/
https://www.ncbi.nlm.nih.gov/pubmed/36979947
http://dx.doi.org/10.3390/biomedicines11030969