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Revisiting the Syndecans: Master Signaling Regulators with Prognostic and Targetable Therapeutic Values in Breast Carcinoma

SIMPLE SUMMARY: Syndecans (SDCs; SDC1 to 4) are integral cell surface proteoglycans that are expressed normally on various types of mammalian tissues. In cancer, SDCs’ expression is dysregulated, impacting the onset and progression of cancer by modulating pivotal signaling pathways involved in biolo...

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Detalles Bibliográficos
Autores principales: Motta, Juliana Maria, Hassan, Hebatallah, Ibrahim, Sherif Abdelaziz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046401/
https://www.ncbi.nlm.nih.gov/pubmed/36980680
http://dx.doi.org/10.3390/cancers15061794