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Minocycline Attenuates Sevoflurane-Induced Postoperative Cognitive Dysfunction in Aged Mice by Suppressing Hippocampal Apoptosis and the Notch Signaling Pathway-Mediated Neuroinflammation

Postoperative cognitive dysfunction (POCD), an important postoperative neurological complication, is very common and has an elevated incidence in elderly patients. Sevoflurane, an inhaled anesthetic, has been demonstrated to be associated with POCD in both clinical and animal studies. However, how t...

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Detalles Bibliográficos
Autores principales: Liang, Junjie, Han, Shanshan, Ye, Chao, Zhu, Haimeng, Wu, Jiajun, Nie, Yunjuan, Chai, Gaoshang, Zhao, Peng, Zhang, Dengxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046414/
https://www.ncbi.nlm.nih.gov/pubmed/36979321
http://dx.doi.org/10.3390/brainsci13030512