The First-In-Class Anti-AXL×CD3ε Pronectin™-Based Bispecific T-Cell Engager Is Active in Preclinical Models of Human Soft Tissue and Bone Sarcomas

SIMPLE SUMMARY: Sarcomas are a group of heterogeneous diseases with a poor prognosis and scarce therapeutic options. Innovative approaches based on novel therapeutic targets are eagerly awaited. AXL, a TAM family tyrosine kinase receptor, recently emerged as an interesting target for several type of...

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Detalles Bibliográficos
Autores principales: Polerà, Nicoletta, Mancuso, Antonia, Riillo, Caterina, Caracciolo, Daniele, Signorelli, Stefania, Grillone, Katia, Ascrizzi, Serena, Hokanson, Craig A., Conforti, Francesco, Staropoli, Nicoletta, Gervasi, Luigia, Di Martino, Maria Teresa, Arbitrio, Mariamena, Nisticò, Giuseppe, Crea, Roberto, Tagliaferri, Pierosandro, Juli, Giada, Tassone, Pierfrancesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046451/
https://www.ncbi.nlm.nih.gov/pubmed/36980534
http://dx.doi.org/10.3390/cancers15061647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046451/
https://www.ncbi.nlm.nih.gov/pubmed/36980534
http://dx.doi.org/10.3390/cancers15061647

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