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Integrative Analyses Reveal the Anticancer Mechanisms and Sensitivity Markers of the Next-Generation Hypomethylating Agent NTX-301

SIMPLE SUMMARY: We thoroughly investigated the experimental and preclinical efficacy of the novel hypomethylating agent (HMA) NTX-301 through comparative analyses with conventional HMAs. By performing multiomics data analyses, we demonstrated the mechanisms of action underlying the anticancer activi...

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Detalles Bibliográficos
Autores principales: Lim, Byungho, Yoo, Dabin, Chun, Younghwa, Go, Areum, Kim, Ji Yeon, Lee, Ha Young, Boohaker, Rebecca J., Cho, Kyung-Jin, Ahn, Sunjoo, Lee, Jin Soo, Jung, DooYoung, Choi, Gildon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046470/
https://www.ncbi.nlm.nih.gov/pubmed/36980623
http://dx.doi.org/10.3390/cancers15061737