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Inhibition of Microglial Activation by Amitriptyline and Doxepin in Interferon-β Pre-Treated Astrocyte–Microglia Co-Culture Model of Inflammation †

Depression may occur in patients with multiple sclerosis, especially during interferon-β (IFN-β) treatment, and therapy with antidepressants may be necessary. Interactions of IFN-β with antidepressants concerning glia-mediated inflammation have not yet been studied. Primary rat co-cultures of astroc...

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Detalles Bibliográficos
Autores principales: Faustmann, Timo Jendrik, Wawrzyniak, Marisa, Faustmann, Pedro M., Corvace, Franco, Ismail, Fatme Seval
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046476/
https://www.ncbi.nlm.nih.gov/pubmed/36979303
http://dx.doi.org/10.3390/brainsci13030493