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Moderate-Intensity Intermittent Training Alters the DNA Methylation Pattern of PDE4D Gene in Hippocampus to Improve the Ability of Spatial Learning and Memory in Aging Rats Reduced by D-Galactose

(1) Background: Aging is the main risk factor for most neurodegenerative diseases, and the inhibition of Phosphodiesterase 4(PDE4) is considered a potential target for the treatment of neurological diseases. The purpose of this study was to investigate the inhibitory effect of moderate-intensity int...

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Detalles Bibliográficos
Autores principales: Zhang, Jinmei, Gao, Qiaojing, Gao, Jun, Lv, Liting, Liu, Renfan, Wu, Yi, Li, Xue, Jin, Yu, Wang, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046546/
https://www.ncbi.nlm.nih.gov/pubmed/36979232
http://dx.doi.org/10.3390/brainsci13030422