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Treatment Strategies for KRAS-Mutated Non-Small-Cell Lung Cancer

SIMPLE SUMMARY: KRAS plays an important role in transmitting signals from growth factors on the outside of the cell to the cell nucleus. It regulates cell proliferation, growth, and survival. The activation of KRAS occurs in multiple tumour types, either directly due to a mutation in the KRAS gene o...

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Detalles Bibliográficos
Autores principales: O’Sullivan, Éabha, Keogh, Anna, Henderson, Brian, Finn, Stephen P., Gray, Steven G., Gately, Kathy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046549/
https://www.ncbi.nlm.nih.gov/pubmed/36980522
http://dx.doi.org/10.3390/cancers15061635