Inhibition of Acid-Sensing Ion Channels by KB-R7943, a Reverse Na(+)/Ca(2+) Exchanger Inhibitor

KB-R7943, an isothiourea derivative, is widely used as a pharmacological inhibitor of reverse sodium–calcium exchanger (NCX). It has been shown to have neuroprotective and analgesic effects in animal models; however, the detailed molecular mechanisms remain elusive. In the current study, we investig...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Hua-Wei, Chu, Xiang-Ping, Simon, Roger P., Xiong, Zhi-Gang, Leng, Tian-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046550/
https://www.ncbi.nlm.nih.gov/pubmed/36979442
http://dx.doi.org/10.3390/biom13030507

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046550/
https://www.ncbi.nlm.nih.gov/pubmed/36979442
http://dx.doi.org/10.3390/biom13030507

Ejemplares similares