Computational Analysis and Experimental Testing of the Molecular Mode of Action of Gatastatin and Its Derivatives

SIMPLE SUMMARY: The glaziovianin A derivative gatastatin, presented as a γ-tubulin-specific inhibitor, could represent a viable chemotherapeutic strategy to solve the specificity issues associated with targeting α and β tubulin. Since gatastatin’s specificity for γ tubulin has not been confirmed by...

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Detalles Bibliográficos
Autores principales: Vottero, Paola, Wang, Qian, Michalak, Marek, Aminpour, Maral, Tuszynski, Jack Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046562/
https://www.ncbi.nlm.nih.gov/pubmed/36980600
http://dx.doi.org/10.3390/cancers15061714

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046562/
https://www.ncbi.nlm.nih.gov/pubmed/36980600
http://dx.doi.org/10.3390/cancers15061714

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