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Advances in PARP Inhibitors for Prostate Cancer

SIMPLE SUMMARY: Recent practice-changing trials have highlighted the importance of polyadenosine diphosphate-ribose polymerase inhibitors (PARPi) in metastatic castrate resistant prostate cancer (mCRPC). PARP plays a quintessential role in repairing deoxyribonucleic acid (DNA) single-strand breaks b...

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Detalles Bibliográficos
Autores principales: Tisseverasinghe, Steven, Bahoric, Boris, Anidjar, Maurice, Probst, Stephan, Niazi, Tamim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046616/
https://www.ncbi.nlm.nih.gov/pubmed/36980735
http://dx.doi.org/10.3390/cancers15061849