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KI04 an Aminoglycosides-Derived Molecule Acts as an Inhibitor of Human Connexin46 Hemichannels Expressed in HeLa Cells

Background: Connexins (Cxs) are proteins that help cells to communicate with the extracellular media and with the cytoplasm of neighboring cells. Despite their importance in several human physiological and pathological conditions, their pharmacology is very poor. In the last decade, some molecules d...

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Detalles Bibliográficos
Autores principales: Chang, Cheng-Wei T., Poudyal, Naveena, Verdugo, Daniel A., Peña, Francisca, Stehberg, Jimmy, Retamal, Mauricio A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046693/
https://www.ncbi.nlm.nih.gov/pubmed/36979346
http://dx.doi.org/10.3390/biom13030411