Structure-Guided Prediction of the Functional Impact of DCLK1 Mutations on Tumorigenesis

Doublecortin-like kinase 1 (DCLK1) is a functional serine/threonine (S/T)-kinase and a member of the doublecortin family of proteins which are characterized by their ability to bind to microtubules (MTs). DCLK1 is a proposed cancer driver gene, and its upregulation is associated with poor overall su...

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Detalles Bibliográficos
Autores principales: Carli, Annalisa L. E., Hardy, Joshua M., Hoblos, Hanadi, Ernst, Matthias, Lucet, Isabelle S., Buchert, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046695/
https://www.ncbi.nlm.nih.gov/pubmed/36979969
http://dx.doi.org/10.3390/biomedicines11030990

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046695/
https://www.ncbi.nlm.nih.gov/pubmed/36979969
http://dx.doi.org/10.3390/biomedicines11030990

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