TRPV6 Calcium Channel Targeting by Antibodies Raised against Extracellular Epitopes Induces Prostate Cancer Cell Apoptosis

SIMPLE SUMMARY: The TRPV6 channel is upregulated in many cancers and is associated with bad prognosis. Despite this fact, no reliable tool to target TRPV6 is known so far. Two prospective antibodies have been generated capable of binding to TRPV6 and thereby transiently activating calcium currents....

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Detalles Bibliográficos
Autores principales: Haustrate, Aurélien, Shapovalov, George, Spriet, Corentin, Cordier, Clément, Kondratskyi, Artem, Noyer, Lucile, Foulquier, François, Prevarskaya, Natalia, Lehen’kyi, V’yacheslav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046753/
https://www.ncbi.nlm.nih.gov/pubmed/36980711
http://dx.doi.org/10.3390/cancers15061825

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046753/
https://www.ncbi.nlm.nih.gov/pubmed/36980711
http://dx.doi.org/10.3390/cancers15061825

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