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Spatiotemporal Regulation of FMNL2 by N-Terminal Myristoylation and C-Terminal Phosphorylation Drives Rapid Filopodia Formation

The actin nucleating and polymerizing formin-like 2 (FMNL2) is upregulated in several cancers and has been shown to play important roles in cell migration, invasion, cell–cell adhesion and filopodia formation. Here, using structured illumination microscopy we show that FMNL2 promotes rapid and highl...

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Detalles Bibliográficos
Autores principales: Lorenzen, Lina, Frank, Dennis, Schwan, Carsten, Grosse, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10046779/
https://www.ncbi.nlm.nih.gov/pubmed/36979484
http://dx.doi.org/10.3390/biom13030548